A young single mother disappears without a trace while visiting her friends' farm in Pocomoke City, Maryland. An investigation suggests she abandoned her children, while her family spends years proving she was murdered and finding her killers.
In the small town of Angier, North Carolina, a man claims he shot his daughter's estranged husband, Christian Griggs, in self-defense. But after investigators close the case, Christian's family discovers evidence that the killing was not justified.
In the town of Iaeger, West Virginia, a beloved town doctor perishes in a deadly house fire - which investigators conclude was arson. But after securing a murder conviction, the prosecutor doubts his own evidence, and joins the fight to free an innocent man.
Investigators in Portage County, Ohio, looking into a shocking double murder, elicit a series of confessions from a group of teens. But years later, the teens recant their statements. Did aggressive tactics send an innocent man to death row?
A California criminal defense attorney, widely known for uncovering corruption, finds himself on trial. Accused of a complex murder-for-hire plot, along with eight others, he fights to clear his name and expose the many holes in the state's case.
Shortly after moving to the rural Texas town of Royse City, a couple is found brutally murdered in their home. Investigators learn that the last person to see them alive had secrets of his own. But some question whether prejudice led police to arrest the wrong man.
In Florida, a dentist is killed by a masked shooter. Media reports link the dentist's wife and stepson to the crime. However, a private investigator presents a different theory about the murder.