During the original air date, Fox was having a "Tribute to The Simpsons" week during which their shows would somehow reference The Simpsons (1989). In this episode, Dan Castellaneta (who voices Homer Simpson) makes a guest appearance. Also, in the first scene inside the lab at the Jeffersonian, an X-Ray of Homer Simpson's head is clearly hanging in the background.
When Cam and Vincent first talk in the lab Cam walks past a posted x-ray. The x-ray is of cartoon character Homer Simpson. Dan Castellaneta, the voice of Homer Simpson, guest stars briefly as Officer Novarro in this episode. (Additionally, the dwarf wrestling match is won by Bumblebee Man, a recurring character in The Simpsons.) A few bars of the Simpson's theme is played at end of the scene with Officer Novarro.