Clint Howard's character has a paranoiac rant in which he describes his fear of renegade Romulans from the future coming to alter the timeline of history. In delivering the message, he also implies that he himself is Spock (calling himself the son of Sarek). This would prove to be a key plotline of Star Trek (2009), directed by series co-creator J.J. Abrams and written by co-creators Alex Kurtzman and Roberto Orci. The movie was officially released in several countries, including the United States, on May 8 2009, three days after this episode aired. He also mentions Khan Noonian Singh who was the main antagonist in the J.J. Abrams directed sequel Star Trek Into Darkness (2013).
There are several Star Trek references in this episode, due to the premiere of the 2009 Star Trek (2009) movie by J.J. Abrams at the time. When Olivia and Peter go to Grayson's house, the number is 1701, like the Starship Enterprise number; Emmanuel Grayson says he is the son of Sarek, which would make him Spock (or his brother); Spock's mother in the Star Trek movies is Amanda Grayson - they share the same surname.