Editor J. Jonah Jameson's son John, the astronaut, has been infected by space spores. They give him super-powers, so Jonah fit him a hero costume as Colonel Jupiter, who turns on Spiderman because of crimes committed by the black goo's creation Venom. Meanwhile Spiderman must handle Eddie, who transformed into that monster and threatens Peter to keep him silent, while Harry finds glory in school theatre. Police captain George Stacy believes in Spidey's innocence. The spores prove addictive and Venom betrays Peter's secret.