Shooting was momentarily halted when the LAPD arrived by foot, car, and helicopter due to a concerned citizen mistaking zombies and actors with prop weapons for gang members battling in the streets.
The LA Fire Department drove into production, in route to a nearby emergency call, mistaking the prop police car for a real one and thinking they had arrived at their destination.
During the auditions to find an actor to play Nash, one actor decided to bring his own real gun and press it against Jack Forcinito's head during the read. (Jack plays the character Frank in the movie.) The guy who brought the gun was politely dismissed.
Being a huge fan of the old Universal monster movies, director Sean Cain made references to those old films with the characters of Frank and Sarah Talbot, played by Jack Forcinito and Nadine Stenovitch. Talbot, of course, is the family name first used in The Wolf Man (1941) by Lon Chaney Jr. and Claude Rains which reoccurred in subsequent sequels featuring Chaney. Elsa Lansing, played by Felissa Rose is based on real life actress Elsa Lanchester who was the bride in Bride of Frankenstein (1935) and last, but not least Jimmy Williams as Henry Glendon is another werewolf reference only this time it's a combination of actor Henry Hull and his Werewolf of London (1935) character Dr. Glendon.
An actor was run over while riding his scooter to set and had to have surgery, thereby delaying shooting for a half day.