When Meg comes down to breakfast after her illness, she wears pajamas. After cutting to a commercial then back to the family eating breakfast, she is wearing her regular clothes.
When Brian talks Meg out of participating in the book burning, the color and position of the books she's holding changes between shots.
In Peter's prayer, he asks God for the cheat codes to Mike Tyson's Punch-Out because he has been stuck on Bald Bull. Mike Tyson's Punch-Out does not contain any cheat codes (aside from minor "easter eggs" that wouldn't benefit gameplay).
Rupert is drawn off-model in this episode.