I've met Michael Cusack's work (and his particular sense of humor) in "Bushworld Adventures", a Rick and Morty-themed special short that still is one of my favorite things on the internet, so I was pretty hyped to learn that he was doing a show for Adult Swim. "Yolo Crystal Fantasy" is what I was expecting: random, bizarre, with a rudimentary art style and causality-driven plots. So yeah, its definitely not a show for everyone and I agree you should be in a certain mood to fully appreciate it and die by laughter-explosion.
The characters, voices, accents (oh man that accent), its original music and their faces are hilarious. Everything is so absurd and unexpected, it's really an excellent comedy ride. I've loved all the episodes of the season, but this finale was the best. It made me laugh and cry. And that's all I'm gonna say about it cause I really don't want to spoil anything.
This guy has a seriously original way to tell a story, and if you add his even-more-original crazy sense of humor and his voice-acting talents you'll have a unique show that you can't miss. Under your own risk, of course. And I'm really eager to see more.