Justine Henin, the women's defending champion, did not return to defend her title due to her retirement from tennis, for personal reasons, earlier in the year.
Serena Williams was the champion on the women's side, winning her third US Open title; she had last won the event in 2002.
Andy Murray and Jelena Jankovic, were making their debuts in Grand Slam finals.
World number ones Rafael Nadal and Ana Ivanovic went out in the semifinal and second round, respectively.