A Portland couple have two children with Pompe disease, a genetic anomaly that kills most before a child's tenth birthday. The husband, John, an advertising executive, contacts Robert Stonehill, a researcher in Nebraska who has done innovative research for an enzyme treatment. He has little money to fund his laboratory, and a thorny personality that drives away colleagues and funders. John and his wife Aileen raise money to help Stonehill's research and the required clinical trials. John takes on the task full time, working with venture capitalists and then rival teams of researchers. Time is running short, Stonehill's angry outburst hinder the company's faith in him, and the profit motive may upend John's hopes. The researchers race against time for the children who have the disease. Written by
John Crowley: The real John Crowley has a cameo in the film as "Renzler Venture Capitalist #2". See more »
When John Crowley first meets Dr. Stonehill in Nebraska, he said that the Dr. had hung up on him the day before yesterday, but goes on to say that his daughter had almost died last week. That is backwards from the earlier scenes, as the daughter was in the hospital after his call. See more »
The story starts with John Crowley(Brendan Fraser) who's two young kids have a deadly disease called Pompa. And are not expected to live long. Much of the heartbreaking of him and his wife(Keri Russell). But John one day decides to try and do something, he goes to see a doctor and scientist Robert Stonehill(Harrison Ford) who's research about the disease could be helpful. And John will help Stonehill set his research, in hopes to make a cure. But will they is the question?
A true story that was very well told. Brendan Fraser performance is so good he almost brings you too tears. Keri Russell also great has the mother. Harrison Ford at times I felt overacted in some scenes,but he was good none the less. A truly great well told story.
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