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Kristin Scott Thomas,
Charles S. Dutton
A Portland couple have two children with Pompe disease, a genetic anomaly that kills most before a child's tenth birthday. The husband, John, an advertising executive, contacts Robert Stonehill, a researcher in Nebraska who has done innovative research for an enzyme treatment. He has little money to fund his laboratory, and a thorny personality that drives away colleagues and funders. John and his wife Aileen raise money to help Stonehill's research and the required clinical trials. John takes on the task full time, working with venture capitalists and then rival teams of researchers. Time is running short, Stonehill's angry outburst hinder the company's faith in him, and the profit motive may upend John's hopes. The researchers race against time for the children who have the disease. Written by
The real John Crowley has a cameo in the film as "Renzler Venture Capitalist #2". See more »
When Patrick Crowley is throwing food to ducks at the lake, he laughs and reveals that he is missing two milky central incisors. At the end of the movie when he is in the hospital taking his medicine, he laughs again revealing that he is missing only one milky central incisor instead of two - the last scene of the movie was filmed before the first. See more »
[Looking at the college-aged kids hired to work under Dr. Stonehill]
These guys make me feel old.
Dr. Robert Stonehill:
Scientists get all sensible & careful when they get old. Young ones like risk, not afraid of new ideas... & you can pay 'em less.
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Harrison Ford still displays great instincts both as an actor and as an executive producer. I believed in his character whole-heartedly, and convincingly-so as the movie unfolded the story. Brendan Fraser is also very convincing as a decent, but desperate and resourceful father. This is a movie that made me want to read the book, research the real issues.
I especially like the way the audience is increasingly drawn in, not only to the family seeking Dr. Stonehill's cutting edge medical research, but, moreover, in to the very lives of other families enduring a plight similar to the family of the main protagonists.
The movie is strong in terms of not over-playing the sentiment, which it would have been so easy to do.
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