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In a distant star system a virus has killed most of the male population and male superiority has all but disappeared in that galaxy. On the prison planet Novella, where female convicts are incarcerated, the inmates are required to engage in fights to the death.
Four beautiful and deadly female gladiators of Novella, overcome their conflicts and try to save their star system from the government group known as the Central, who wish to destroy the balance of male-female dominance in the galaxy by the spreading of the virus. They get help from a space adventurer, and face up space pirates in an intergalactic fight for freedom.