When asked about his most difficult scene, Jeremy Renner revealed that it was the motorcycle ride with Rachel Weisz behind him in Manila, because he was responsible for the two of them. At the press conference of the film, Weisz was asked about this particular stunt, "How was it to ride on a motorcycle through Manila with Jeremy Renner?" and she said that "It was really terrifying! Jeremy never told me when we were in Manila, but that was the scariest stunt for him because he was responsible for my life. He didn't tell me that in Manila, thank god, because I would have been like, 'Oh, my god!' I just had to surrender and hold on. I didn't have to act. It just was terrifying".
Daniel Craig visited his wife Rachel Weisz during their shoot in Manila. Producer Frank Marshall was glad to see them together, saying: "It was pretty cool to have James Bond on the 'Bourne' set with Aaron Cross. We had a great time. It was really fun."
The location of Aaron Cross at the wilderness outpost as seen on the display at Drone Command is 61 48 28.54 -142 49 06.17 (or 61.632507,-142.968292). This is in the Wrangell-St.Elias National Park and Preserve in Chitina Alaska, approximately half way between the peaks of Regal Mountain and Presidents Chair at an altitude of 8900 feet.
Before this movie was seriously considered, director Paul Greengrass (who helmed two earlier installments of this series) jokingly suggested to make a fourth Bourne movie called "The Bourne Redundancy".
The generic name of Sterisyn Morlanta's new cognitive enhancing drug Requiel, seen printed on the poster behind the Candent spokesperson is Alprazolam, which is actually the generic name for Xanax, a popular tranquilizer.
Matt Damon as Jason Bourne has a photographic cameo twice in the film in order to help establish this film as part of the series. First in the beginning of the film, when the agency is talking about what they're going to do as Bourne is still at large and a file of Bourne is seen with Damon's picture with it. The last time is just before Cross and Shearing are in an airport and Cross is watching the news and Bourne's picture comes up when the News Anchor mentions his name.
The character Jason Bourne alias David Webb from three novels by Robert Ludlum was licensed out to Eric Van Lustbader to continue the life and adventures of that character, starting with The Bourne Legacy. However, as with most films in this series, this movie is an original screenplay using only the title of that novel.
In the begining a pack of wolves are shown attacking an elk, however the only Elk in Alaska are limited to a few Islands, and not near where Cross was supposed to be, i.e. near Wrangell-St. Elias Park.
This is the second time Oscar Isaac has played a character who has something to do with the CIA and gets killed within the first 30 minutes and his death is caused by an explosion. The first time being 'Body of Lies'