Jackie's marriage is strained, as is her relationship with O'Hara after the intervention; Akalitus warns the staff that nearby hospitals have closed down, straining the staff and resources; Zoey publicly confesses her affair with Lenny.
Eddie tells Jackie he can't keep lying to Kevin, whom he now considers a real friend. Akalitus announces that All Saints is vying for a visit from Michelle Obama and confides to Jackie that O'Hara is looking for work at another hospital. Coop tries to bury the hatchet with Sam. The rift between Jackie and O'Hara softens when Jackie tells her that she'll follow her to any hospital just to be near her. Kevin tells Jackie his buddy Eddie called and is out of a job and asks if she can put in a good word for him at All Saints.
Much to Jackie's surprise, Kevin's younger sister, Tunie, shows up in the girls' bedroom, freshly hungover and tragically heartbroken after being dumped by her pilot boyfriend. On their way to work, Jackie tells Eddie she thinks Kevin installed Tunie to monitor her in the wake of his intervention. Lenny prepares Zoey a romantic picnic lunch only to crack her tooth when she bites into a sandwich where he's hidden his house key. Zoey talks things over with God, who's set up a makeshift piano bar in the ambulance bay. At the hospital, a Jewish Orthodox husband fights ...
Jackie's back in the swing of things, having re-hidden her stash of pills in the basement and mended fences with O'Hara. Zoey's working her first double and Jackie worries about her burning out. Lou, an out-of-work salesman, comes into the hospital and wins everyone over. O'Hara accepts the title of ER chief, which sparks a competitive streak in Coop. Kevin invites Eddie to a backyard barbecue to celebrate his new job. When Jackie gets home, she sees empty closets and drawers and panics-did Kevin leave her? She finds out he went to an Al-Anon meeting and the drawers ...
Jackie is on edge after realizing the stash of pills she stole from Bill the epileptic drug dealer is quickly dwindling. With a head of steam, Jackie confronts Eddie about his recent text exchanges with Kevin's younger sister, Tunie. Eddie maintains that it's completely innocent, while making the point that Jackie has no leg to stand on. Coop remains determined to battle O'Hara for the ER Chief title, but suffers a huge emotional blow when his mothers announce they're divorcing. Lou, the down-on-his-luck salesman, returns to the ER much worse for the wear. Akalitus ...