A distinctive visual motive is the patterns on the characters' clothing/skin staying the same. The patterns are developed as a full-screen image and then sent to the production house, where the characters are modified to fill the patterns in over the character skin/clothing. With this technique, when a character moves, their patterns do not follow but are displayed as a "static" background.
C.H. Greenblatt thought Truffles was too coarse a character to be used in a story, so the writers decided to keep her appearance in the show as minimal as possible: "a little Truffles goes a long way."
Panini originally had an outfit which only revealed her face (which was to have pointy ears), and was going to bully Chowder in a manner similar to Rugrats (1990)'s Angelica Pickles. But C.H. Greenblatt disliked unctuous obnoxious characters like Angelica, and so decided to make Panini cuter and sweeter: he made the pointy ears bunny ears, and made her have a crush on Chowder; since Chowder is not old enough for girls, Greenblatt felt this would make the romance much funnier.
C.H. Greenblatt originally thought of giving Mung Daal an Indian accent, since he was named after an Indian dish (mung daal is a Indian spicy soup). He decided against it since he didn't want to attract any racial controversy.
An episode was planned where Mung Daal (Dwight Schultz) would be framed for a crime, and would enlist some old friends to go on a mission to clear his name. The episode was meant to be a homage to Schultz's classic series The A-Team (1983), and would have brought in fellow cast members Dirk Benedict and Mr. T (the latter having established a career in voice acting). Unfortunately it had to be shelved.
Kevin Michael Richardson was meant to be Shnitzel's original voice, but he did only one episode and was replaced with John DiMaggio from then onwards as he was busy working on other projects at the time.