The character played by Avi Rothman has the name Steve Lemmaduche, obviously relating to the fact that he took Connor's role on CFI: Hotlanta. Connor is played by actor and member of the Broken Lizard, Steve Lemme
The disease the Lone Diner says he is dying of, Schistosomiasis, is a parasitic "flatworm" infection carried by freshwater snails in Africa. Schistosomiasis is one of the most common parasitic disease in primitive areas. Schistosomiasis is almost never directly fatal, but a chronic years-long infection can cause organ damage, several cancers, and in children can cause developmental problems. Schistosomiasis rather easily cured with Praziquantel.
Lance Henriksen compares the potential resurrection of Conner's character on CFI: Hotlanta to the X-Files. Henriksen had a major role as ex-FBI agent Frank Black on the X-Files as well as its sister series Millenium.