Warehouse 13 has been destroyed, Pandora's Box has been opened, and quite possibly the only hope left in the world lies in the use of a dangerous, evil artifact with the ability to turn back time.
Pete, Myka, and Claudia each travel to save a loved one who has fallen victim to an artifact, Mrs. Frederic and Steve head to the Vatican to investigate the Brotherhood, and Artie has an impossible showdown with Brother Adrian.
H.G. Wells returns to help Pete and Myka with an artifact that's forcing confessions out of criminals all while earthquakes are beginning to shake the Warehouse.