Yes. Here are a couple of them:
Barnabas Collins (Johnny Depp) is an 18th century gentleman businessman from just before the Revolutionary War, who was transformed against his will into a vampire and buried in a tomb for two centuries. After he finally emerges, uncovered by construction workers in the year 1972, he seeks out his descendants as well as some long-ago foes and a possible lost love. He has been alive this whole time, very hungry, and with no idea what's going on outside. Barnabas is one vampire who is just as frightened of our times as we are of him, says producer Richard D. Zanuck. Two-hundred years later, he's suddenly walking into the town he saw being built and seeing girls in skirts and cars for the first time. Despite his confusion, he's still a ladies man. In some sense he can be a terrifying killer; on the other hand, women have a weakness for him, and he has a weakness for women. He can be a well-mannered, well-meaning vampire most of the time, until his stomach is empty or someone challenges his beloved Collins family.
Here's that family:
Dr. Julia Hoffman (Helena Bonham Carter), prim and proper psychiatrist, who has taken up residence with the Collins family to care for their troubled youngest boy David. She's been there for years, working with him. He still claims he sees ghosts and talks with his dead mother. Hoffman is crazy but brilliant. She's eccentric and definitely likes a drink or two. She's definitely a little bit off her rocker and is a woman with a lot of secrets herself.
Carolyn Stoddard (Chloë Grace Moretz), a cousin to David Collins, is your typical early-1970s teenager. She likes her music and magazines and does not like anyone in her family. She likes to keep her door closed and keep to herself. She's pretty normal, but appearances can be deceiving.
Angelique Bouchard (Eva Green) is a witch who has known Barnabas since the 1700s, when they had an affair that went sour. She is the one who cursed him to be a vampire and locked him in that box. Since he has been away, Angelique has made it her life's mission to destroy the Collins family. When Barnabas turns up again after all these years, she's not very happy to see him.
David Collins (Gulliver McGrath). Lonely, confused, and neglected by his pompous father, David has no one to confide in except his bizarre psychiatrist and the dead people he claims to see.
Victoria Winters (Bella Heathcote) arrives to become David's new governess, only to find herself swept up in the vampire-witch melodrama. When Barnabas meets Victoria, he is instantly reminded of the woman he lost in the 1700s, before he was cursed to be a vampire. Is she the reincarnation of his doomed lover Josette du Pres?
Mrs. Johnson (Ray Shirley), the mostly blind and deaf maid, has been with the Collinses for decades. You might find her polishing a piece of silverware with a slab of baloney because she thinks its a polishing cloth.
Willie Loomis (Jackie Earle Haley), groundskeeper, is a slightly more competent servant than Mrs. Johnson, but that's not saying much. He's the guy who takes out the trash, mows the lawns, and fixes the cars, except he's usually so drunk and so disinterested that he doesn't take his job seriously anymore. The lawn is overgrown, the house has fallen into disrepair, and all the cars are on cinder blocks. His heart is definitely not in the job anymore.
Roger Collins (Jonny Lee Miller), scion of the once-great Collins family, is one of the main reasons the aristocratic clan has fallen into such disgrace. He's a creepy, self-centered guy who likes to order Willie around and pretend the family is still on top of his game. Not only is he a bad father to David, but he is a poor manager of whatever meager wealth the family retains. When Barnabas shows up and has some very specific ideas about how to make things right, the two are obviously going to bump heads.
Elizabeth Collins Stoddard (Michelle Pfeiffer), mother of Carolyn Stoddard and mother-figure to David, is the one adult member of the Collins clan who is at least slightly competent. Elizabeth is the rock of the family, the matriarch. She's the keeper of the Collins history and a fierce protector of what remains of her family. She's the one who insists on the best care for the children, even though money isn't what it used to be. She's a very strong woman who unfortunately has been dealt a very difficult deck. With a witch perpetually trying to destroy her and a long lost vampire relative turning up to reclaim control, there's a lot for her to handle.