| Grey DeLisle | ... | Mandy / Carol (voice) | |
| Greg Eagles | ... | Grim / Sperg (voice) | |
| Richard Steven Horvitz | ... | Billy / Billy's Dad / Cave Harold (voice) (as Richard Horvitz) | |
| Vanessa Marshall | ... | Irwin (voice) | |
| Dee Bradley Baker | ... | Chocolate Cow / Arachnosaur / Clarence / Dark Elf Archer / Spider #2 (voice) | |
| Maxwell Atoms | ... | Jeff the Spider / Mystery Announcer / Man (voice) | |
| Jane Carr | ... | Pud'n (voice) | |
| Chris Cox | ... | Principal Goodvibes (voice) | |
| Henry Gibson | ... | Lord Pain (voice) | |
| Jennifer Hale | ... | Gladysaur (voice) | |
| David L. Lander | ... | Curtis (voice) (as David Lander) | |
| Phil LaMarr | ... | Mr. Spleen (voice) | |
| Rachael MacFarlane | ... | Mindy / Velma's Mom / Eris (voice) | |
| Michael McKean | ... | Kalgoron (voice) | |
| Renee Raudman | ... | Ms. Butterbean (voice) | |
| Armin Shimerman | ... | General Skarr (voice) | |
| James Sie | ... | Plain Cow (voice) | |
| Kari Wahlgren | ... | Velma Green the Spider Queen (voice) | |
| Fred Willard | ... | Boogey (voice) | |
| Dave Wittenberg | ... | Velma's Dad / Spider #1 (voice) |
| Episode Crew |
Directed by | |||
| Matt Engstrom | |||
| Gordon Kent | |||
| Juli Murphy | (supervising director) (as Juli Hashiguchi) | ||
| Kris Sherwood | |||
Writing credits | ||
| Maxwell Atoms | (written by) | |
| Maxwell Atoms | (creator) | |
Produced by | |||
| Maxwell Atoms | .... | executive producer | |
| Shaun Cashman | .... | supervising producer | |
| Louis J. Cuck | .... | producer | |
| Brian A. Miller | .... | executive producer: Cartoon Network Studios | |
| Jennifer Pelphrey | .... | supervising producer: Cartoon Network Studios | |
Original Music by | |||
| Gregory Hinde | |||
| Drew Neumann | |||
Casting by | |||
| Kris Zimmerman | |||
Art Direction by | |||
| Marc Perry | |||
Production Management | |||
| Jay Bastian | .... | executive in charge of production: Cartoon Network | |
| James Silverman | .... | production manager | |
| Tony Tedford | .... | post-production supervisor | |
Art Department | |||
| Alex Almaguer | .... | storyboard artist | |
| Mark Bachand | .... | prop designer | |
| Anna Chambers | .... | prop designer | |
| Michael Diederich | .... | storyboard artist (as Mike Diederich) | |
| Chris Headrick | .... | storyboard artist | |
| Clay Morrow | .... | storyboard artist | |
| Tara Whitaker | .... | storyboard revisionist | |
Sound Department | |||
| Jesse Aruda | .... | sound editor (as Jesse Arruda) | |
| Brad Brock | .... | sound re-recording mixer | |
| Timothy J. Garrity | .... | re-recording mixer (as Tim Garrity) | |
| Jim Hearn | .... | dialogue editor | |
| Chris Hoetger | .... | machine room operator | |
| Glenn Oyabe | .... | sound editor (as Glenn E. Oyabe) | |
| Karie Gima Pham | .... | recording studio manager | |
| Erik Sequeira | .... | sound re-recording mixer | |
| Robert Serda | .... | recording engineer | |
| Kris Zimmerman | .... | recording director | |
Animation Department | |||
| Maxwell Atoms | .... | character designer | |
| Sandy Benenati | .... | animation checker | |
| Joe Binggeli | .... | background painter | |
| Russell Calabrese | .... | sheet timer | |
| Serapio Calm | .... | character designer | |
| Bill Flores | .... | background designer | |
| Frank Homiski | .... | character cleanup | |
| Eddy Houchins | .... | sheet timer | |
| Becca Ramos | .... | background designer (as Rebecca Ramos) | |
| Phil Rynda | .... | character designer | |
| Brian Smith | .... | color stylist | |
| Don Watson | .... | background painter | |
| Eva Wu | .... | character cleanup | |
Editorial Department | |||
| Anna Granfors | .... | assistant editor | |
| Illya Owens | .... | picture editor | |
| Alicia Parkinson | .... | post-production coordinator | |
Music Department | |||
| Gregory Hinde | .... | composer: theme music | |
| Drew Neumann | .... | composer: theme music | |
Other crew | |||
| Antonio Gonella | .... | director of production technology | |
| Ben Pile | .... | production assistant | |
| Pietro Piumetti | .... | production assistant (as Pietro 'Pappy' Piumetti) | |
| Shalonda Ware | .... | production accountant | |
| Main series | Episode guide | Full cast and crew |
| IMDb TV section | IMDb Animation section | IMDb USA section |