Lana absorbs Clark's powers and becomes a super-woman. In Superman comics, Lois Lane has, in several occasions, temporarily received Superman's powers and assumed the alter ego of Superwoman afterwards, most notably in Grant Morisson's "All-Star Superman". Superman's powers were also transfered to Lois in "Lois & Clark: The New Adventures of Superman (#3.7)" (1995) , where she becomes the Ultrawoman.
Lionel and Lex both give Biblical allusions. Lionel warns Clark with the story of Samson and Delilah, in which Samson trusted his lover Delilah with the secret to his immense strength, only to have her betray him. Lex compares himself to the Apostle Paul, who became a changed man after being struck blind by lightning (though blinded by a bright light - revealed to be Jesus, according to the official account) while on the road to Damascus.
Brainiac appears as black liquid. This is the first time he appears in any form since Fallout, where he appeared as the Black box and was turned to ash. He is shown to be immune to kryptonite in earlier appearances, but in this episode it seems to affect this portion of him.
Chloe mentions Eric Summers. Eric Summers was portrayed by Shawn Ashmore in 2 other episodes. Aaron Ashmore is Shawns twin brother who plays Jimmy Olsen.
The black liquid of Project Scion has formed from the ashes of the Kryptonian black box. These ashes were seen in Fallout.