Frankie is very busy today. She has to do several errands, pick up Mac, Bloo, Wilt, Eduardo, and Coco, and defend Madame Foster in a trial against Jackie Khones. While doing this, Frankie runs into Cheese, who keeps unintelligently screaming out that he's "gotta go," but no one knows where exactly. When Bloo sees that Ed has lost his marbles, he thinks that Cheese is a brain-sucking alien out to suck the brains of Earth. He tries to send a message into outer space telling the aliens that Cheese is captured and their mission is failed. Meanwhile, Ed is loose on the streets, absentmindedly causing mayhem, with Wilt trying to stop him. Also, the bus gets towed and Mac and Madame Foster try to get it back. In the end, everyone and Jackie Khone except for Frankie are thrown in jail and Cheese is returned to Louise. Written by
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Gotta go, gotta go, gotta go, gotta go!