Splice (2009) Poster



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Those really are Delphine Chanéac's eyes in her performance as adult Dren. The space between her eyes was digitally widened to create this odd effect.
Special effects designers Howard Berger and Greg Nicotero developed 11 different versions of Dren for the film.
Adrien Brody and Sarah Polley were Vincenzo Natali's first and only choices for Clive and Elsa.
Vincenzo Natali first got the idea for the film when he saw a picture of a mouse with a human ear growing on its back.
A Vodka bottle in the lab is labeled to contain a specimen named "BOGIE + BACALL", a reference to classic film couple Humphrey Bogart and Lauren Bacall.
The main scientist characters, Clive and Elsa, are named as an homage to Bride of Frankenstein (1935), a similarly themed movie. Colin Clive played Dr. Henry Frankenstein while Elsa Lanchester played Mary Wollstonecraft Shelley/The Bride.
Vincenzo Natali wanted to make the film after the success of his first film Cube (1997). But the technology hadn't reached the point yet where Natali could give it the treatment it deserved. He shelved the project for ten years, after which he felt the time had finally come.
To help with her posture as adult Dren, Delphine Chanéac performed in high heels.
Delphine Chanéac and Abigail Chu, who play the creature Dren as a child and an adult, both had to shave their heads for this film.
The highest grossing English-language Canadian film of 2010.
Shot in forty-three days.
The gestation cell that Clive and Elsa use to splice Dren has the acronym BETI placed conspicuously on the front of the machine. BETI stands for Biomechanical Extroutero Thermal Incubator. However, interestingly the word "BETI" means daughter in Urdu and Hindi, spoken in large parts of Pakistan and India.
The poster above Clive and Elsa's bed at home says "They're coming!" in Japanese.
Vincenzo Natali's hair turned grey through the filming, apparently because it was such a gruelling shoot.
The two genetically spliced organisms introduced in the beginning of the film, Fred and Ginger, are references to the classic singing and dancing duo Fred Astaire and Ginger Rogers.
Dren has cross-shaped pupils.
The name DREN is the word NERD in reverse. N.E.R.D. is also the laboratory where both Clive and Elsa work (it stands for Nucleic Exchange Research & Development).
Elsa and Clive drive an AMC Gremlin, possibly the 1977 model.
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Would be Dark Castle Entertainment's first horror film to finally receive a fresh rating on Rotten Tomatoes as the previously released films were critically panned.
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The trivia item below may give away important plot points.

Delphine Chanéac only gets one line, right at the end of the film.

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