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Splice (2009)

R  |   |  Horror, Sci-Fi  |  4 June 2010 (USA)
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Ratings: 5.8/10 from 75,998 users   Metascore: 66/100
Reviews: 355 user | 364 critic | 35 from

Genetic engineers Clive Nicoli and Elsa Kast hope to achieve fame by successfully splicing together the DNA of different animals to create new hybrid animals for medical use.



(screenplay), (screenplay), 3 more credits »
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Complete credited cast:
Dren (as Delphine Chaneac)
Simona Maicanescu ...
Joan Chorot
William Barlow


Two young rebellious scientists are told by their employers to halt groundbreaking work that has seen them produce new creatures with medical benefits by splicing together multiple organisms' DNA. They decide to secretly continue their work, but this time splicing in human DNA. Written by Anonymous

Plot Summary | Plot Synopsis


She's Not Human ... Not Entirely. See more »


Horror | Sci-Fi

Motion Picture Rating (MPAA)

Rated R for disturbing elements including strong sexuality, nudity, sci-fi violence and language | See all certifications »

Parents Guide:




| |



Release Date:

4 June 2010 (USA)  »

Also Known As:

Hibrid  »

Filming Locations:


Box Office


$26,000,000 (estimated)

Opening Weekend:

$7,385,277 (USA) (4 June 2010)


£239,538 (UK) (30 July 2010)

Company Credits

Show detailed on  »

Technical Specs


Sound Mix:

| |


Aspect Ratio:

1.85 : 1
See  »

Did You Know?


Vincenzo Natali's hair turned grey through the filming, apparently because it was such a gruelling shoot. See more »


When Ginger and Fred meet in the case at the shareholders' meeting, they began to hiss and protract their claws and fangs. From behind, Ginger's fang is already out, and Fred begins to push his out. In the next shot, Ginger pushes her fang out for the first time. See more »


Clive Nicoli: Why the fuck did you make her in the first place? Huh? For the betterment of mankind? You never wanted a normal child because you were afraid of losing control.
See more »

Crazy Credits

The cast credits and finally the title are scattered throughout the opening credits, instead of appearing consecutively. See more »


Referenced in Switch (2011) See more »


Zeppelin Interpolation
Written and Performed by Bob Wiseman
Courtesy of The Artist
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Frequently Asked Questions

See more (Spoiler Alert!) »

User Reviews

What's With You People?
8 July 2011 | by (United States) – See all my reviews

Three fourths of these reviews hate the movie and whine about the idiot decisions of the scientists. Well of COURSE they made idiotic decisions! Where's the film if they made perfectly sane decisions? What kind of film is that?

I actually thought the film was effing brilliant. I think it took a familiar premise and retooled it. The performances of Adrien Brody and Sarah Polley were exemplary, as always. I saw it for Sarah Polley as she is one of my favorite actors and one of the most underrated ones out there today. The actress that played Dren was also strong and had the perfect mix of human, alien, and innocence.

The film addresses many scientific issues, but does so with a moral and emotional center. I like that the film doesn't pull punches and I like that there are consequences for the actions of the scientists. I thought the complex relationship of the couple and their creation was skillfully rendered and and excellently acted.

Was it flawed? Sure. But it was also really kick ass and I'd see it again in a heartbeat.

If you want your horror sci-fi movies neat and tidy and pedestrian this probably isn't for you.

44 of 57 people found this review helpful.  Was this review helpful to you?

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