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Splice (2009)

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Genetic engineers Clive Nicoli and Elsa Kast hope to achieve fame by successfully splicing together the DNA of different animals to create new hybrid animals for medical use.



(screenplay), (screenplay) | 3 more credits »
2,060 ( 18)
4 wins & 23 nominations. See more awards »




Complete credited cast:
Dren (as Delphine Chaneac)
Gavin Nicoli
Simona Maicanescu ...
Joan Chorot
William Barlow


Two young rebellious scientists are told by their employers to halt groundbreaking work that has seen them produce new creatures with medical benefits by splicing together multiple organisms' DNA. They decide to secretly continue their work, but this time splicing in human DNA. Written by Anonymous

Plot Summary | Plot Synopsis


They Created A Monster See more »


Drama | Horror | Sci-Fi

Motion Picture Rating (MPAA)

Rated R for disturbing elements including strong sexuality, nudity, sci-fi violence and language | See all certifications »

Parents Guide:




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Release Date:

4 June 2010 (USA)  »

Also Known As:

Hibrid  »

Filming Locations:



Box Office


$26,000,000 (estimated)

Opening Weekend USA:

$7,385,277, 6 June 2010, Wide Release

Gross USA:

$16,999,046, 1 August 2010
See more on IMDbPro »

Company Credits

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Technical Specs


Sound Mix:

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Aspect Ratio:

1.85 : 1
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Did You Know?


A Vodka bottle in the lab is labeled to contain a specimen named "BOGIE + BACALL", a reference to classic film couple Humphrey Bogart and Lauren Bacall. See more »


In the first scene when Clive and Elsa take Dren to the barn, it is night, but when they go inside, there is sun streaming through the skylights. See more »


[techno music playing]
Clive Nicoli: This retarded, fascist, über music is the fuckin' problem. It's got us thinking in circles.
[turns on jazz music]
See more »

Crazy Credits

The cast credits and finally the title are scattered throughout the opening credits, instead of appearing consecutively. See more »


Referenced in The Tonight Show with Jay Leno: Episode #21.90 (2013) See more »


Written and Performed by Holy Fuck
Courtesy of XL Music Ltd / 4AD Music Ltd
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Frequently Asked Questions

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User Reviews

Interesting Science Fiction with Intense Issues
7 June 2011 | by See all my reviews

SPLICE has a lot of interesting themes going for it. The issues of raising a child, accepting gender identity and trying to maintain an objective perspective when something you love is the subject of study are all very strongly represented in the story. There are some great rock star science moments that make the film fun and the technology is entertaining if you find it interesting. The main characters Clive and Elsa are pretty much raising a science project through the first two acts. When the experiment becomes self sufficient and gets the intelligent sense to question authority, things get tough. The background story of a company working to harvest miracle genes off bio-engineered organisms secures a solid foundation for the main characters to build on. The film presents motives that are amoral, unethical and rebellious. The story is mostly unflinching and some people in the audience do feel awkward about what they are seeing. DREN is a fantastic character that goes through some drastic evolution. At times it seems like you can side with Elsa and dislike Clive and then you might reconsider that when further events unfold. Every character in this film deals with some seriously brutal events. There are some light and even silly moments to get grounded on and it makes the tough stuff that much more enjoyable when the time comes. If you're willing to take the ride and follow through, SPLICE will guarantee a good time or at least some interesting coffee table conversation. I cant recommend watching this film enough.

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