Cristina is still in her slump and turning mean, Izzie finally confronts Ava/Rebecca, and Meredith's anger with her therapist is challenged by a patient with a Cinderella story.



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Episode cast overview, first billed only:


Meredith's therapist tries a different tactic in not allowing her to give up and quit her therapy, while Cristina's therapy consist of taking it out on everyone around her. In an effort to turn over a new leaf, Sloan's therapy consists of being loved for his mind instead of his body, while Bailey counsels her child for hitting other children in day care, and both Derek and the Chief are getting the cold shoulder from the ladies in their life. Written by Moviedude1

Plot Summary | Plot Synopsis

Plot Keywords:

lesbian kiss | See All (1) »


Drama | Romance


TV-14 | See all certifications »




Release Date:

15 May 2008 (USA)  »

Company Credits

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Technical Specs


Sound Mix:


Aspect Ratio:

1.78 : 1
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Did You Know?


Every episode is named after a song. This episode refers to either the Black Crowes' or Maroon 5's "Losing my Mind" See more »


Dr. Lexie Grey: I forgive you.
Dr. Meredith Grey: Lexie.
Dr. Lexie Grey: No. I forgive you. I forgive you for treating me like crap, and I forgive you for letting your friend treat me like crap.
Dr. Meredith Grey: Lexie...
Dr. Lexie Grey: I don't know how you get up in the morning, I honestly don't. Our dad abandoned you. And your mom by all accounts was the meanest person ever and you can't let Derek love you, and it all really, really sucks. But ever since I knew you existed, I had this fantasy about my big sister, and you have failed on every occasion to live up to that ...
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Cosy In The Rocket
(Main Title Theme)
Written by Carim Clasmann and Galla Durant
Performed by Psapp
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User Reviews

Jumped the Shark
1 October 2008 | by (United States) – See all my reviews

I think Grey's Anatomy has jumped the shark with this episode. This is the one. I always thought that ER was a better show, but this episode solidified that to me.

They're right about the title "Losing My Mind" because the writers/producers have lost their mind right here. The two same-sex characters hooking up (kissing) is a desperate move on their part. My interpretation was it was not done as normal character development but instead for the shock value they hoped it would bring to the show. The

The Meredith back-and-forth thing with Derek is old, boring, and predictable. She can't commit, she wants to commit. ENOUGH!

I think Katherine Heigl was right about not getting good material in Season 4. Nobody did. It was a waste of everybody.

I will watch the season ending, but I doubt I'll be back for Season 5. Bye.

3 of 6 people found this review helpful.  Was this review helpful to you?

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