House and Cuddy are flying back to the US from an international conference in Singapore. While en route a mysterious disease strikes one passenger and an epidemic unfolds, causing House to diagnose in midair since they have missed the halfway mark by passing the north pole. Back in Princeton, Wilson and House's lackeys have a confusing case of what is ailing a woman who came into the clinic and proceeded to have a seizure. Written by
Did You Know?
Pej Vahdat appears in this episode, he is best known for his role as an intern in Bones (2005). The next episode contains two more Bones interns and a guest appearance. See more
The pen House uses in the plane was supposed to be permanent, but after changes in camera angles and scenes, the penmanship changes, especially the size of the letter P, which suggests that the writing was erased and rewritten. See more
Dr. Gregory House
Tell the pilot to dive until we can club baby seals out of the window.
Features Modern Marvels
Hope for the Hopeless
Written by Alison Sudol
, Hal Cragin
, Lukas Burton
Performed by Alison Sudol See more