Seven of the voice actors in "Placebo" were hired from an open audition at the Connecticut School of Broadcasting in Wellesley Hills, Massachusetts, including the co-star Karen Coltin.
The voice of the production assistant with the clapboard who says "Placebo Outtakes, take 1" is Dorin Connell, co-producer of Placebo and wife of Writer/Director Jim Connell
'Goldbrick' is defined as "anything supposed to be valuable but which turns out to be worthless". Goldbrick Industries, the creator of "Placebo" appear four years later as the holders of the "Kaishwa" patent in Jim Connell's 2006 film "Saul Goodman".
There are 3 national magazines featured during the introduction of Goldbrick Industries. Psychology Today shows "pop psychology" and "junk science" tablets being mixed, US News calls them "Fool's Gold", and Time Magazine asks "Is Goldbrick Good for America" with a picture showing an FBI raid on their headquarters.