Real-life murderer Ed Gein inspired the character Norman Bates in the original Robert Bloch novel 'Psycho'; Gein also inspired the character of Jame Gumb (Buffalo Bill) in Thomas Harris' novel 'The Silence of the Lambs' which featured Anthony Hopkins in the film version.
Anthony Hopkins actually met Alfred Hitchcock when he was younger. Hopkins was accompanied by his agent who introduced him to Hitchcock in a restaurant.
In the end scene, a crow lands on Hitch's shoulder, indicating that his next project will be The Birds. That film, and his relationship/obsession with leading lady Tippi Hedren were the basis for another film about Hitchcock, The Girl, broadcast this same year.
Coincidentally, in this film Helen Mirren portrays the wife of a famous film director when, in reality, she's married to a famous film director, namely, Taylor Hackford.
Among the actors who were considered or interviewed for the role of Alfred Hitchcock during the long preproduction were Oliver Platt, Richard Griffiths, Alfred Molina, Paul Giamatti, Philip Seymour Hoffman, Bill Murray and Johnny Depp.
Tony Goldwyn, Tony Shaloub, Steve Guttenberg, Brad Garrett, Mark Strong and Rob Riggle were among the many actors seen/considered to play Lew Wasserman.