Dr. Meredith Grey: Wow, you and George were really going at it last night.
Dr. Isobel "Izzie" Stevens: [Spits out water] What?
Dr. Cristina Yang: The laughing, the drinking, the music. Okay, nobody, I mean me, needs to hear George's rendition of Sexy back at 3:00 in the morning.
Dr. Isobel "Izzie" Stevens: [laughs] Yeah, yeah. You should have said something or you know, banged on the wall.
Dr. Cristina Yang: It's like living in a youth hostel.
Dr. Meredith Grey: Well, the important thing is that she and George made up. You did, right?
Dr. Alex Karev: [Interrupts] I need to use your bathroom
Dr. Meredith Grey: Why?
Dr. Alex Karev: Cause O'Malley's puking in mine.
Dr. Cristina Yang: Youth hostel.
Dr. Isobel "Izzie" Stevens: I had sex last night. With the wrong person. But the thing is, it didn't feel wrong; at the time. It felt like; something was falling into place. So what do I do?
Dr. Addison Montgomery: What am I? The go to person for adultery?
Dr. Isobel "Izzie" Stevens: No. Just, I just don't know what to do.
Dr. Addison Montgomery: You stop. That's what you do.
Dr. Isobel "Izzie" Stevens: Are you sure? I mean, how do you know that it didn't feel so right because.... It's God's plan.
Dr. Addison Montgomery: God wants you to be an adulterer?
Dr. Isobel "Izzie" Stevens: God got a virgin pregnant by magic. God is not playing by the rules.
Dr. Isobel "Izzie" Stevens: Messing up. It's what makes a person. It's how we learn, where we find joy. And the things you don't plan for are things you never see coming.
Dr. Meredith Grey: The thing about plans is they don't take into account the unexpected. So when we're thrown a curve ball, we have to improvise. Of course, some of us are better at it than others. Some of us have to move on to plan B and make the best of it. And sometimes what we want is exactly what we need, but sometimes what we need is a new plan.