- Seth Cohen: [Ryan has woken up in the hospital after getting hurt in the earthquake, Seth is sitting in a chair in his room] Although, you're going to have to wrap your head about the fact that we're really brothers now... We're blood brothers.
- Ryan Atwood: You... donated blood?
- Seth Cohen: Eh, I had an extra few pints flowing through my veins. It was no big deal.
- Ryan Atwood: Hm. You're not a big fan of needles.
- Seth Cohen: Nor of fainting, it turns out. But, the bank was a little low and us O negative guys gotta stick together.
- Ryan Atwood: Hm. It's weird, cause all of the sudden I have this strange urge to listen to Death Cab and read comic books.
- Seth Cohen: For real?
- Ryan Atwood: No. I'm kidding.
- Kaitlin Cooper: [as Julie and Frank are unsure about kissing in front of her] Go for it. There's been a frigging earthquake.
- Seth Cohen: You're asking me to use tools and exert myself physically. I think we both know where this is going.
- Seth Cohen: If we could've turned this into a body-swap comedy, we could've squeezed another year or two out of this.