The televisions in the Buy More store will always display images or footage that will relate to what is occurring within the episode. For example, in season one, episode two, "Chuck Versus the Helicopter", the televisions display footage of helicopters.
During an interview with The A.V. Club, Vik Sahay said that he first auditioned for the role of Morgan, and when the auditions came down to just himself and Joshua Gomez, and Gomez got it, the producers instead offered Sahay the then-smaller role of Lester. Lester has since become a more prominent character than he was in the pilot.
In a 2013 National Public Radio interview, Zachary Levi said that he was almost in the Broadway musical production of "Young Frankenstein", but he had to give up the opportunity, because the pilot for this show got picked up as a series.
In season two, episode eleven, "Chuck Versus Santa Claus", there are several references to Die Hard (1988). The LAPD officer in charge is Al Powell, (played by Reginald VelJohnson), who also eats Twinkies. He responds to the F.B.I. Agent who asks "Who's in charge here?", just like in the movie. Al Powell also calls his brother, the store manager, Mike Powell, and uses a line from the film "How ya holding up in there, partner?"
Natalie Martinez was to join the cast after the pilot episode as Kayla Hart, a love interest for Chuck. Martinez appeared in the cast promotional pictures, but her character was written out before she could appear on the show.
Many references are made to the movie Spies Like Us (1985). The bug used in several episodes is called a GLG-20, which is the designation given to undercover operatives in the movie. Emmett Millbarge is named after the two main characters in the movie, first name taken from Chevy Chase's Emmett Fitz-Hume, and last name taken from Dan Aykroyd's Austin Millbarge; this is also the order they are introduced in the film. In an episode, Chuck poses as a doctor, and references a scene from the movie, where doctors go through greeting each other by saying "Doctor, Doctor". Chevy Chase has a guest role in the show. In the movie, one of the actors playing the Tadzhik Highway Patrolman has the name Costa-Gavras, and the name of the Communist country featured in "Chuck Versus the Angel of Death" has the name Costa Gravas. Also, while Chuck and Sarah are watching television, Spies Like Us (1985) comes on, and Sarah (Yvonne Strahovski) comments "not again". Another reference is from one of the episodes featuring Chevy Chase; in which is featured an underground bunker disguised as a drive-in movie theater.
In seasons one through three, Big Mike (Mark Christopher Lawrence) has a marlin on the wall of his office that features in several episodes. In season four, Morgan Grimes (Joshua Gomez) has a "Billy the Big Mouth Bass" on the wall behind his desk.
In season four, episode seventeen, "Chuck Versus the First Bank of Evil", there are actually two references to Lost (2004). The first is when Vivian (Lauren Cohan) receives the bank card at Volkoff Industries, in which the card displays the famous numbers from Lost (2004) 4815162342. The second reference is at the National Bank of Macau. Guillermo Chan, the head of the bank, is played by François Chau, who also played Dr. Pierre Chang from the Dharma Initiative in Lost (2004).
In season five, episode three, "Chuck Versus the Frosted Tips", Morgan (Joshua Gomez) dodges the tranquilizer darts in the same fashion Neo (Keanu Reeves)) does in The Matrix (1999). Carrie-Anne Moss, who plays Gertrude Verbanski, played Trinity in The Matrix (1999).
At the close of the second season, declining ratings, and stiff competition from the other networks, had indicated that Chuck would be cancelled. But, due to petitioning from its loyal fan base, specifically aimed at one of its sponsors (Subway), the show was renewed for a third season, in an unprecedented partnership between NBC and the sandwich chain helping to cover the production costs. Chuck continued to face cancellation for its subsequent seasons, with its fifth season becoming its final season, beginning October 28, 2011, and ending on January 27, 2012, with a two hour finale.
In season four, episode ten, "Chuck Versus the Leftovers", Chuck's mom (Linda Hamilton) says "Come with me, if you want to live!" This is a direct quote from Arnold Schwarzenegger in Terminator 2: Judgment Day (1991), in which Hamilton also starred.
When Dolph Lundgren appears in the season four opener, "Chuck Versus the Anniversary", he makes several references to his character Ivan Drago from Rocky IV (1985). He does so when interrogating John Casey (Adam Baldwin), telling him, "I must break you", as well as threatening the team saying, "If they die, they die."
Yvonne Strahovski (Sarah Walker) and Ryan McPartlin (Dr. Devon "Captain Awesome" Woodcomb) provided the voices of Peg Mooring and Clutch Powers in Lego: The Adventures of Clutch Powers (2010) between seasons of this show.
In the season four opener, Chuck (Zachary Levi) and Morgan (Joshua Gomez) constantly use "Tangiers" as their code word to run. This is possibly a reference to The Bourne Ultimatum (2007), when Jason Bourne is in Tangiers, Morroco, and there is a lot of running.
Guest stars Linda Hamilton, Robert Patrick, Summer Glau, and Brian Thompson have starred in the Terminator franchise. Linda Hamilton played Sarah Connor in The Terminator (1984) and Terminator 2: Judgment Day (1991). Robert Patrick played the T-1000 in Terminator 2: Judgment Day (1991). Summer Glau played Cameron Phillips in Terminator: The Sarah Connor Chronicles (2008), and Brian Thompson played a punk in The Terminator (1984).
In season one, episode two, "Chuck Versus the Helicopter", Chuck is listing a series of things he knows from the intersect. One of them is a reference to Lost (2004), when he says "Oceanic Flight 815 was shot down by a surface to air...."
In season three, episode eighteen, "Chuck Versus the Subway", Alex (Casey's daughter) runs away from Casey (Adam Baldwin) after he tries to save her, and he yells, "I am your father!" Alex (Mekenna Melvin) responds with "That's impossible!", which is a reference to Star Wars: Episode V - The Empire Strikes Back (1980).
In season four, episode twelve, "Chuck Versus the Gobbler", Sarah (Yvonne Strahovski) says, "I love a good suicide mission.", which is likely a reference to her character Miranda Lawson in Mass Effect 2 (2010).
In season four, episode nine, "Chuck Versus Phase Three", Richard Chamberlain plays "The Belgian", who wanted to take away Chuck's memories, emotions, and personality, making him one hundred percent spy. Richard Chamberlain starred in The Bourne Identity (1988) as Jason Bourne, a spy who lost his entire memory and personality, and became one hundred percent spy.
In season three, episode seven, "Chuck Versus the Mask", Chuck goes to a building to save Shaw (Brandon Routh). The building that was used, is the same building used in Mighty Morphin Power Rangers (1993), as the command center.
In the beginning of season four, episode five, "Chuck Versus the Couch Lock", three men show up to John Casey's funeral and proceed to provoke his body to make sure he's dead. This is a reference to Charade (1963), in which the same three methods are used to wake up another dead man at his funeral.