John C. Reilly created the character of Dr. Steve Brule. He brought his own wardrobe. The reading glasses were a pair that he bought at Rite Aid. "Brule" is a word that Reilly and his friends had created to refer to the feeling in one's stomach when drinking too much alcohol.
In the green-screen segments, Eric can sometimes been seen with his legs in awkward positions. This is because that studio has a low ceiling and Eric is 6 feet, 6 inches tall so he often has to crouch to avoid hitting his head. He also has to sometimes put his head in awkward positions to avoid the studio lights' glare in his eyeglasses.
The title of the show is a mixture of ideas. Bob Odenkirk suggested to have "Tim and Eric" in the title, Eric Wareheim suggested the name "Awesome Show", and Tim Heidecker suggested the name "Great Job". The comma (,) and the exclamation point were added then for comedic effect.
Tim Heidecker and Eric Wareheim won the 2008 Webby Awards for best actor as part of the comedy team of "Tim and Eric". Film & Video awards winners are selected for recognition based on excellence in the following criteria: Concept & Writing, Quality of Craft, Integration, Overall Experience.
At Tim's funeral in season finale "Embarrassed", Eric sums up Tim's life by calling him "an average sized man." In "Resurrection", the following season premiere, "An average sized man" is written on Tim's gravestone.