Joshua Leonard appears as a film professor (and a suspect). He was one of the filmmakers and stars of The Blair Witch Project (1999), the movie from which this episode seems to have been derived.
Amanda Fuller (Lori Mueller) plays an incarnation of The First Evil on Buffy the Vampire Slayer in the seventh season. Earlier in the series, The First Evil tried to convince Angel (David Boreanaz) to end his own life.
Amanda Fuller (Lori Mueller) went on to play Kristin Baxter in Last Man Standing, from the second season on, replacing Alexandra Krosney who had played the character in the first season; Krosney played Amy Cullen, the daughter of Booth's boss, in episode 1x20, "The Graft in the Girl." (Note the episode numbers, 1x20 and 2x10.) Jonathan Adams, who played Dr. Goodman in the first season of this show, also played on Last Man Standing, as Chuck Larabee.