Leonard Hofstadter and Sheldon Cooper are both brilliant physicists working at Caltech in Pasadena, California. They are colleagues, best friends, and roommates, although in all capacities their relationship is always tested primarily by Sheldon's regimented, deeply eccentric, and non-conventional ways. They are also friends with their Caltech colleagues mechanical engineer Howard Wolowitz and astrophysicist Rajesh Koothrappali. The foursome spend their time working on their individual work projects, playing video games, watching science-fiction movies, or reading comic books. As they are self-professed nerds, all have little or no luck with popular women. When Penny, a pretty woman and an aspiring actress originally from Omaha, moves into the apartment across the hall from Leonard and Sheldon's, Leonard has another aspiration in life, namely to get Penny to be his girlfriend. Written by
When beauty meets the brains.
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Did You Know?
Amy Farrah Fowler always has her elbows and knees covered because Mayim Bialik
is Modern Orthodox. Except in S05E03 & S07E21. See more
Howard states many times that he has a Masters degree in engineering from the Massachusetts Institute of Technology. However, it is also stated often that Howard never left his mother's home before he married. While MIT does have distance learning programs, Howard's degree program would have had required him to attend classes on campus, which would have required him to have moved out of his mother's house prior to the start of the series. See more
[repeated line when Sheldon tells a sarcastic joke
One of the final cards to appear in the credit sequence is the vanity card for Chuck Lorre Productions. In keeping with his practice on "Dharma and Greg" and "Two and a Half Men", there is a different message on the card each week, written by Chuck Lorre himself. See more
History of Everything (Instrumental)
Composed by Barenaked Ladies
Performed by Barenaked Ladies
Played during the end credits See more