In the movie commentary, it is mentioned the town at the end with the fair is loosely based on a real town known as Sighisoara, Romania. Sighisoara is also known as the birthplace of Vlad the Impaler, the real Count Dracula and is the only inhabited citadel in Europe, outside Corsica (where all the citadels are inhabited).
Near the beginning of the movie, when the hotel guests are first seen arriving, Dracula (Adam Sandler) mentions that the hotel has been in operation since 1898. It is also shown that Mavis's mother was killed by a mob in approximately 1895 (based on a family portrait showing Mavis at around 1 yr old with both of her parents). The original book, Bram Stoker's Dracula, was written in 1896 and released in 1897. So this movie actually uses a chronological order following the original Dracula story as if it were a telling of true events.
(at around 1h 20 mins) At the end of the movie, at Mavis's birthday party, the label on the record on the turntable reads "Oh! who said so - Sung by - Mr. Charles Penrose". This was a real pre-WWI record.
In the beginning of the movie, during the Columbia Pictures logo, The Torch Lady turns into Mavis as a bat. You know it's Mavis not Dracula because Dracula has red eyes in bat form while Mavis has blue eyes.
During one of the of the sequences in the forest, one of the trees has a spiderweb and the spider's body looks like a skull, similar to the recurring Skulltulla monsters from the The Legend of Zelda videogames