The scene where Pitka (Mike Myers) and Jane Bullard (Jessica Alba) are on the plane and said she turned for advice from gurus when her dad died, is based on a real life situation by Mike Myers after his father died.
Used throughout the movie as a faux Indian greeting, "Mariska Hargitay" is actually the name of an actress. When Guru Pitka greets his followers after his presentation at the Pitka Ashram, Hargitay herself appears in a brief cameo scene which makes light of her role as Detective Olivia Benson in Law & Order: Special Victims Unit (1999).
There is an extra scene with Kanye West being interviewed at a hockey game to which Mike Myers has brought him. Each time the interviewer gives the microphone to Kanye, Mike Myers leans in and keeps repeating, "Don't say it, don't say it!" Mike Myers was onstage with Kanye West when Kanye made his infamous George W. Bush does not like Black people,' statement.
During the scene where Guru Pitka and Rajneesh are singing More Than Words, the man waving a lighter on Guru Pitka's "hybrid pillow", is a real member of crew. He also appears at the beginning of the movie, after Guru Pitka sings "9 to 5" when he takes his pillow off camera.
The opening scene is set in a location named Harenmahkeester, as declared by a large sign. This prop reappears in the reality show Junk Raiders (2009), Episode 4, where it's salvaged to act as a headboard.