In her Season 1 DVD commentary, Janet Waldo mentions how a number of the advanced things shown are just preliminary versions of things that are now used. Things like the "food-a-rac-a-cycle" being basically a microwave oven, and moving sidewalks, which are often seen in airports.
Judy mentions having to do homework on geopolitics, Esperanto, and Greek calculus. While Greek calculus isn't (yet) real, geopolitics and Esperanto have grown as areas of study. Geopolitics has naturally grown with historic events between the 1950s and 2020s, while Esperanto has grown to two million speakers of the language, many of whom learned it with the advent of the Internet and social media.
The mustache, vocal intonation, and dialogue ("Ye-e-es-s?") of the robot salesperson seems to be an allusion to Frank Nelson's various roles from The Jack Benny Program (1950), which also served as the inspiration for Dan Castellaneta from The Simpsons (1989).
George Jetson's is a Digital Index Machine operator for Cosmo Spacely's company, Spacely Sprockets.
Jane's age is given as 33, Judy's said to be 15, and Elroy says he's 6 & a half.