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Love & Other Drugs (2010)

R  |   |  Comedy, Drama, Romance  |  24 November 2010 (USA)
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Ratings: 6.7/10 from 133,992 users   Metascore: 55/100
Reviews: 211 user | 217 critic | 38 from Metacritic.com

A young woman suffering from Parkinson's befriends a drug rep working for Pfizer in 1990s Pittsburgh.



(screenplay), (screenplay), 2 more credits »
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Nominated for 2 Golden Globes. Another 1 win & 5 nominations. See more awards »



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Cast overview, first billed only:


Maggie (Hathaway) is an alluring free spirit who won't let anyone - or anything - tie her down. But she meets her match in Jamie (Gyllenhaal), whose relentless and nearly infallible charm serve him well with the ladies and in the cutthroat world of pharmaceutical sales. Maggie and Jamie's evolving relationship takes them both by surprise, as they find themselves under the influence of the ultimate drug: love. Written by Twentieth Century Fox

Plot Summary | Plot Synopsis


Accros aux nuits sans lendemain ou dépendants l'un de l'autre? (Addicted to one-night stands or dependent on one another?) (French)


Comedy | Drama | Romance

Motion Picture Rating (MPAA)

Rated R for strong sexual content, nudity, pervasive language, and some drug material | See all certifications »

Parents Guide:





Release Date:

24 November 2010 (USA)  »

Also Known As:

Hard Sell  »

Filming Locations:


Box Office


$30,000,000 (estimated)

Opening Weekend:

$9,739,161 (USA) (26 November 2010)


$32,357,532 (USA) (11 February 2011)

Company Credits

Show detailed on  »

Technical Specs


Sound Mix:



Aspect Ratio:

1.85 : 1
See  »

Did You Know?


The film is based on a book - Hard Sell: The Evolution of a Viagra Salesman - by former Pfizer rep Jamie Reidy. He says the book is a "jumping off point" and that there is no love interest in it as he removed all of those references, thinking that his mother would read the book. See more »


When Jamie is handed the list of dates by Dr. Knight's secretary, Gail, he drops the paper on the desk, seemingly indifferent while listening to Gail. In the immediately following shot, responding to her question, it is in his hands and he is reading it. See more »


Jamie Randall: [on the bus] I need you.
Maggie Murdock: Please go away.
Jamie Randall: I drove a really long way to say that!
Maggie Murdock: What, am I supposed to be impressed?
Jamie Randall: I don't know, yes?
See more »


References Speed (1994) See more »


Also Sprach Zarathustra
Written by Richard Strauss
Performed by Symphony Orchestra Baden Baden - Ferdinand Leitner
Courtesy of Selectracks / Denon Classics
See more »

Frequently Asked Questions

See more (Spoiler Alert!) »

User Reviews

An easy formula that insults my intelligence (once again)
23 June 2011 | by (Brazil) – See all my reviews

Here's a recipe to make a romantic comedy about an annoying couple:

01) Jake Gyllenhaal's butt. 02) Anne Hatthaway's tits. 03) A lot of sex scenes to attract men audience that are there just for their wives/girlfriends that wanted so bad to watch it because, you know, men are sexual. 04) A lot of drama scenes to attract their wives/girlfriends that, until that moment, wasn't interested about Anne Hatthaway's tits because, you know, women are sensible. 05) An infamous discussion about love, leading to nowhere. 06) A very uncommon disease but not cancer, because cancer is now cliché, so... let's talk about Parkinson's Disease, that happens 99,9% of the time into old people population, but they decided to make a movie about the 0,1% of young people that can be affected because, you know... 27 years old Anne Hatthaway with Parkinson's Desease is now prettier than 81 years old Clint Eastwood. 07) A (un)funny-fat annoying ugly character to make comedy time effective. 08) Some unnecessary war between sexes for later discussions. 09) Some lack of rationality. 10) Confident-hard-as-rock characters that are able to hurt each other but deeply they have sensible souls. 11) And finally: the birth of love no matter its obstacles.

That's it. You just have to mix it all and the success is granted and then the movie is able to receive unbelievable 7.3 of general ratings.

Awful movie using the same awful formula for an awful easy money return. Not even Jake Gyllenhaal's legs can save it.

43 of 80 people found this review helpful.  Was this review helpful to you?

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