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Love & Other Drugs (2010)

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A young woman suffering from Parkinson's befriends a drug rep working for Pfizer in 1990s Pittsburgh.



(screenplay), (screenplay) | 2 more credits »
1,526 ( 140)
Nominated for 2 Golden Globes. Another 1 win & 3 nominations. See more awards »



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Cast overview, first billed only:
Dr. Stan Knight
Trey Hannigan
Dr. James Randall
Nancy Randall
Dr. Helen Randall


Maggie (Hathaway) is an alluring free spirit who won't let anyone - or anything - tie her down. But she meets her match in Jamie (Gyllenhaal), whose relentless and nearly infallible charm serve him well with the ladies and in the cutthroat world of pharmaceutical sales. Maggie and Jamie's evolving relationship takes them both by surprise, as they find themselves under the influence of the ultimate drug: love. Written by Twentieth Century Fox

Plot Summary | Plot Synopsis


Accros aux nuits sans lendemain ou dépendants l'un de l'autre? (Addicted to one-night stands or dependent on one another?) (French)


Comedy | Drama | Romance

Motion Picture Rating (MPAA)

Rated R for strong sexual content, nudity, pervasive language, and some drug material | See all certifications »

Parents Guide:





Release Date:

24 November 2010 (USA)  »

Also Known As:

Hard Sell  »

Filming Locations:



Box Office


$30,000,000 (estimated)

Opening Weekend USA:

$9,739,161, 28 November 2010, Wide Release

Gross USA:


Cumulative Worldwide Gross:

See more on IMDbPro »

Company Credits

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Technical Specs


Sound Mix:



Aspect Ratio:

1.85 : 1
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Did You Know?


The anti-Parkinson's drugs Sinemet and Ropinirole, mentioned in the film, can cause sexual hyperactivity and hyperarousal in some patients as a side-effect. See more »


The position of the box of corn flakes changes during the conversation about changing report card grades. See more »


Jamie Randall: Let's just say in some alternate universe, there's a couple just like us, okay? Only she's healthy and he's perfect. And their world is about how much they're going to spend on vacation or who's in a bad mood that day, or whether they feel guilty about having a cleaning lady. I don't want to be those people. I want us. You. This.
See more »


Heaven Is A Place On Earth
Written by Ellen Shipley and Rick Nowels
Performed by Belinda Carlisle
Courtesy of Virgin Records Ltd. / Geffen Records
Under license from Universal Music Enterprises
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Frequently Asked Questions

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User Reviews

Slow Start, Great Finish... Anne Hathaway is Wonderful
8 December 2010 | by See all my reviews

The movie starts out as a generic and even pedestrian romantic comedy and appears to be headed in the typical cliché driven direction but, fortunately, evolves in to something more. Jake Gyllenhaal's character and his alleged "funny" fat side kick are established almost purposefully as illustrations of what's wrong with most romantic comedies. It's Anne Hathaway's character that is the catalyst for the transformation from two dimensional rom-com to something deeper and more enjoyable. As she is fleshed out (pun intended because the more Anne Hathaway nudity the better) her character forces both Gyllenhaal's character and the film itself to grow (almost Viagra like). What follows is a deep, sometimes moving and genuinely interesting film. Commentary about battling illness, life and enjoying the moment are all relevant and poignant. Even supporting characters are given moments to shine. Oliver Pratt's drug rep has a wonderful scene delivered over dinner and there's even a smart drunken ramble explaining what is wrong with being a doctor and a commentary on the state of the Hippocratic Oath. From an emotionless and even tedious start, this film surprised me and is worth the price of a ticket.

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