This is the second episode in the series to be told solely from the point of view of the protagonist, The first was Hungry (1999). Scully and Doggett are only shown when he comes into contact with them.
Although Danny Trejo has many tattoos, the spider's web he sports on his hand was not his own and was drawn on.
Gillian Anderson and Robert Patrick were particularly pleased with this episode as their characters barely feature in it and the onus of all the work fell on guest star Joe Morton.
Joe Morton and Robert Patrick have previously worked together on Terminator 2: Judgment Day (1991) as Miles Dyson and the T-1000 respectively.
This was developed around about the same time that a film with a similar theme - Christopher Nolan's Memento (2000) - was in production.