Tom Paris' line "I'm a pilot, not a doctor !" at the 26 minute mark is a parody of the running gag that all doctors have said in the Star Trek series. It started with McCoy on the original Star Trek, and moved on through every series since.
The Doctor's message at the end of this episode seems to suggest that the Romulan Telek R'Mor from "Eye of the Needle" did not, or could not, in fact make arrangements to send Voyager's personal letters to their families in 2371 after his death in 2367, which would have informed Starfleet of the ship's location in the Delta Quadrant.
Although the Dominion is referenced in several other shows, this is the only one to reference the Dominion War and the only direct mention of the Dominion on the series. This makes sense, since Voyager was stranded in the Delta Quadrant long before the start of the Dominion war, remained there for its duration, and did not return until after it had ended.