Jeri Taylor intended the Native American colony in this episode to be the home of Voyager character Chakotay, though this was never mentioned on screen.
Wesley Crusher's last appearance on the show. He would make a short cameo in Star Trek: Nemesis (2002), but a lot of it was cut from the final release. Wesley has a brief cameo in Season 2 of Star Trek:Picard.
The Pueblo Revolt of 1680 mentioned in the episode, where Picard's ancestor was one of the soldiers leading the attack on Indian settlers, was a real historical event.
This episode lays the groundwork for the DMZ, contested territories between the Federation and the Cardassian Empire. People being forced from their homes would lead to the formation of the Maquis, a recurring plot thread in Star Trek: Deep Space Nine (1993) and Star Trek: Voyager (1995).
Lakanta says he's been awaiting Wesley's arrival for two years. This would tie in with the events of The First Duty (1992), when Wesley participated with Nova Squadron's cover-up over the death of a cadet. This was probably the catalyst for Wesley becoming disillusioned with Starfleet. Even Admiral Brand, who oversaw the legal proceedings, informs Beverly here how far Wesley has fallen.