Robin Williams, a long time Star Trek (1966) fan, had to opt out of the role of Prof. Rasmussen to play Peter Pan in Steven Spielberg's Hook (1991).
"A Matter of Time" won an Emmy Award for Outstanding Individual Achievement in Special Visual Effects, sharing it in a tie with Conundrum (1992).
Picard makes an analogy about Khan Noonien Singh from Space Seed (1967) and Star Trek II: The Wrath of Khan (1982). This is the only mention ever made of Khan on TNG.
Rasmussen's question to Riker concerning what he thought was innovative about the USS Enterprise-B is the first canonical reference to that starship.