This is the only time that Sam leaps into a non-human.
Coincidentally, Caroline Goodall (Dr. Leslie Ashton) just happens to share the same last name as Jane Goodall, who is considered the world's foremost expert on chimpanzees; both were born in London, England, but are not related.
In an episode of the TV series I Dream of Jeannie (1965), Fly Me to the Moon (1967), Larry Storch played an astrochimp named Sam who was accidentally turned into a human.
In the original history, Bobo and Cory died of massive head trauma on January 25, 1961.