Monty Python's Flying Circus (1969) was one of the earliest comedy programs to satirize Margaret Thatcher by saying her brain was at her knee. At the time Thatcher was a Member of Parliament. Her Prime ministership was 9 years away at the time of the airing of this episode.
During a sketch with John Cleese where they played a pair of Pepperpots, Graham Chapman suddenly went off script and screamed "Burma!" for no reason. Cleese then asked Chapman, in character, why he did that, to which Chapman replied, in character, "I panicked!". It was later decided it was too funny not to include.