Adorable teenager Keith Foster suddenly starts bleeding terribly during a ride with dad's Porsche his cheeky girlfriend Pam got him to let her steer. Loving widowed father Foster fears ex-junkie Pam got his good boy on drugs, but Keith tests clean, yet shows a confusing set of symptoms, mainly liver-problems. After various negative tests, either hyper-rare hepatitis E -possibly caught on foreign travels- or lupus (immunity turning against the patient himself) seem likely. Chase cleverly manages to save his eye which suddenly went blind from blood cluttering. House, who is even grumpier and ruder after accepting a dare from Cuddy to earn a week off clinic duty by going a week without his painkiller to make sure he's not getting addicted, holds out on medication for lupus as it would render hepatitis incurable, alas needlessly for so long the boy now needs a liver transplant, but also insists to elaborate Keith's apparent hallucination about being tortured by a certain Jules, which ... Written by
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This is the first time that Lupus is offered as a possible diagnosis. See more
When it is revealed that House is suffering the effects of opiate withdrawal Dr. Cuddy states that it is because House is addicted to the Vicodin. However just because someone is experiencing withdrawal after stopping an opiate or opioid (opiate is a term used to describe the naturally occurring narcotics in opium which are mainly codeine and morphine. Whereas opioid is a term used for the semi-synthetic analgesics like hydrocodone (Vicodin, Lortab and Norco), oxycodone (Percocet and OxyContin) and Hydromorphone (Dilaudid), as well as the fully synthetic narcotic analgesics like methadone and fentanyl) does not mean that they are addicted to the drug, it just means that their body, mainly the brain and nervous system, has become tolerant to the drug. While only some people who use opiates and opioids become addicted to them (meaning they take the drug for the high). Whereas everyone who takes an opiate or opioid for more then a couple weeks will become tolerant to the drug (meaning that the drug is similar to chemicals secreted in the brain, mainly endorphins and dopamine our bodies natural painkiller and "feel good hormone". In fact endorphins are very similar to morphine both chemically and in its effects on the nervous system) so since these drugs are a lot like those chemicals secreted in our brain, the brain stops making these chemical neurotransmitters. But when you suddenly stop taking opiates or opioids it throws out brain into a chemical imbalance which is what withdrawals are and once our brain is able to catch up and start producing normal levels of endorphins and dopamine then the withdrawal subsides. So to sum it up once again, going into withdrawal after the cessation of opiates or opioids does not necessarily mean one is addicted to them. See more
[Dr. House, to delay a surgery, has violently sneezed and coughed all over the sterile field
There's no way we can do the surgery now...
Written by Dave Mason
Performed by Joe Cocker See more