Meredith wants to learn more about Derek, but he remains cagey. Meanwhile, a supposedly psychic patient proves bothersome, Alex must convince a young girl to agree to a life saving operation, and Cristina is conflicted about her pregnancy.



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Episode cast overview, first billed only:
Dr. Richard Webber (credit only)
Zoey Glass
Mr. Duff
Tommy Walker
Devo Friedman
Seymour Glass


Meredith grows increasingly dissatisfied with fact that she knows nothing about Derek's life. Meanwhile, Alex treats a patient whose religious beliefs jeopardize her chances for recovery, and Izzie contemplates reconnecting with her estranged mother. Also, a pregnant woman in her 40s who's been diagnosed with cancer disagrees with Cristina's medical advice. And the interns are mystified by a patient who's being treated for seizures and who thinks he's psychic. Written by Alex

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Drama | Romance






Release Date:

15 May 2005 (USA)  »

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Aspect Ratio:

1.78 : 1
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Did You Know?


Every episode of the show is named after a famous song. "Save Me" is a song by Aimee Mann. See more »


Devo "Esther" Friedman refuses to take a porcine heart valve because of her strong Orthodox Jewish religious beliefs. Also, right before her surgery she requests that a rabbi bless her - and the rabbi that the hospital supplies is female. In Orthodox Judaism, female rabbis are not considered legitimate, and most Orthodox rabbis would not object to using the porcine valve, since life takes precedence above all else. However, Devo/Esther's particular branch of Orthodox Judaism and/or her personal religious convictions could certainly account for any perceived discrepancy. See more »


Dr. Meredith Grey: Where are we?
Dr. Derek Shepherd: I'm gonna tell you. All right. My mother's maiden name, Maloney. I have four sisters. I have, uh, nine nieces. Five nephews. I like coffee ice cream, single-malt scotch, occasionally a good cigar. I like to fly fish. And I cheat when I do the crossword puzzle on Sunday. And I never dance in public. Um, favorite novel, The Sun Also Rises. Favorite band, The Clash. My favorite color is blue. I don't like light blue, indigo. The scar right here on my forehead, that's why I don't ride...
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References The Courtship of Eddie's Father (1969) See more »


Think (Vocal)
Performed by Dan Bierton & Charlie Waddington
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User Reviews

A step back
18 December 2008 | by (Italy) – See all my reviews

Alongside the pilot, Save me is the least interesting episode of Grey's Anatomy's first year, primarily because of lazy writing that panders to clichés without the gusto required to make fun of them, which was the main joy of previous shows.

As usual, the main storyline concerns the least appealing character, namely Meredith, who is unhappy about not knowing much regarding Derek, despite the fact they have sex every night. Subplots worth noticing: Cristina has to come to terms with her unwanted pregnancy, Izzie considers getting back in touch with her estranged mother, and everyone at the hospital is startled by a patient with seizures who claims to be psychic.

That last element (the "psychic" guy) is the classic "potentially inexplicable case" gimmick that could ruin a show. In this case, it actually works in the episode's favor, since the silly plot line is handled with the right kind of humor/seriousness balance that is sorely missing elsewhere. Even Sandra Oh, normally the most reliable cast member, does petty much nothing important this time around, leaving it to Patrick Dempsey to save the day (and the last few minutes of the episode) with his natural charm and endearing wit. But hey, with only one more episode until the end of the season, such a misstep isn't that smart a move.

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