The Act 1, Scene 2 title card reads "Does He or Doesn't He?" This is a reference to a 1950s/60s advertising campaign for Clairol Hair Coloring: "Does She or Doesn't She? Only Her Hairdresser Knows for Sure!"
During the week this episode aired, Jane Leeves also appeared as Marla Penny in the final episode of Seinfeld (1989).
While waiting in the hospital waiting room, Frasier picks up a magazine and says, "Oh look, Dad. That cute Tricia Nixon is getting married". Tricia Nixon, daughter of former President Richard M. Nixon, married Harvard Law graduate Edward Finch Cox on June 12, 1971.
Towards the end in the hospital, Frasier says, "Her loss" and gestures like comedy legend, Jack Benny.
Niles (David Hyde Pierce) and Frasier (Kelsey Grammer) are competing for the same woman and Niles says, "I saw her first." However Frasier told Roz (Peri Gilpin) he met her before Martin (John Mahoney) introduced her to Niles, so Frasier saw her first--not Niles.