Frank Schroeder is hitchhiking and is picked up by a motorist in the Southwest. Schroeder kills the motorist in cold blood. Now, the FBI has launched a manhunt for Schroeder and puts him on the agency's Ten Most Wanted list. The criminal hooks up with a young Mexican woman. He is now in San Antonio, where there are rumors that a reclusive woman has a fortune in diamonds hidden in her home. Erskine and Rhodes try to trace Schroeder's bloody trail, which will result in the death a pawn broker. Can the FBI bring the criminal to justice before it's too late for others?
—Bill Koenig