Filming of the pilot episode featured a scene in which Jolene Blalock, as T'Pol, bared her navel. This required removal of Blalock's navel piercing ring. According to interviews given by Blalock, the ring proved very difficult to remove, and forced Blalock (in full Vulcan make-up) to visit a nearby tattoo-body piercing shop to have it removed.
In Capt. Archer's cabin, there is a photo on the wall of a Pan American World Airways Lockheed Constellation. Gene Roddenberry was, at one time a pilot for Pan Am. Also displayed next to the Constellation photo is a small statuette of Zefram Cochrane with his arm reaching out, presumably a smaller-scaled model of the 20-meter-tall statue of Cochrane that Geordi described to Cochrane himself in Star Trek: First Contact (1996).
During filming of the pilot, veteran Star Trek actors Brent Spiner and Jonathan Frakes visited Scott Bakula on the set to give him advice about what to expect while working on the series. Both actors later guest starred on "Enterprise"'s fourth season.