This is one of the few episodes to show an exterior shot facing down the stairs to the front door of Cheers.
The title is a play on title of the classic self-help book, How to Win Friends & Influence People by Dale Carnegie.
This is the second of three times Sam has a bloody nose. First being Showdown Part 2 (1983).
Lilith uses the line, "See the U.S.A. in your Chevrolet". This was a slogan and line from a long-running jingle from the fifties and sixties that was extremely familiar to the baby boomers who formed the cast and the audience of Cheers. It was a response to the post-WWII conversions of massive factories from building armaments to consumer goods and the rekindling of the auto industry. Affordable cars, a booming middle class economy, and the newly created Interstate Highway system, resulted in the idea of taking cross-country vacations. To contemporary viewers of Cheers, Lilith's reference was emotionally and visually evocative, to the point of the jingle playing in many viewer's heads.
Cliff says he is having surgery at New England Presbyterian. There is no such hospital. There is a New England Baptist located in Boston. The exterior shots of the hospital is of the Massachusetts General Hospital.