It's mentioned that the Crawler originated out of Central City, which is also the home of Barry Allen, the Silver Age Flash. Ironically, after the series' cancellation, Ashley Scott played Huntress again 16 years later on The Flash (2014) in "Crisis on Infinite Earths: Part Three (2019)".
When Reese runs into Huntress at the crime scene, he mentions wanting to develop a criminal profile in order to find the Crawler. Shemar Moore's most recognizable role is FBI profiler Derek Morgan on Criminal Minds (2005), a character he played from 2005 to 2016.